The World Health Organization (WHO) Cancer Department International Cancer Research Agency (IARC) recently said that Asba may be declared "may cause cancer to humans."This news has aroused heated discussions on the Internet. As the most widely used sugar substitute substitution in sugar -free drink, if Asba is carcinogenic, can everyone drink sugar -free drinks happily?
Today’s popular science will introduce the relevant knowledge of Asba’s sweetness in detail.
After decades of research on artificial sweeteners (ASW) to reduce the incidence of obesity and diabetes, Asba was discovered in 1965 and eventually pushed to the market in 1981.Asba is 150-200 times sweet than sugar, so it does not increase the calories of food and beverage products.
According to data from the US Food and Drug Administration (FDA), Asba’s daily acceptable intake (ADI) is 50 mg/kg, and the European regulatory agency recommends that adults and children Asba’s sweet ADI is 40 as 40Milligram/kg.In all parts of the world, Asba can be found in more than 6,000 products, including food and drinks, cough potions and some toothpaste, which shows that this kind of chemicals are everywhere in many daily necessities.
Although most of the food and beverage products containing Asba’s sweet food and beverage products are promoted as a "health" or "diet" alternative to sugary products, these products have never been confirmed to reduce the risk of diabetes or obesity.On the contrary, some evidence shows that the taste of sugar -containing and artificial sweet beverages will increase hunger, which will lead to weight gain.
After consumption of Asba, this chemical is hydrolyzed and absorbed in the gastrointestinal tract (GI).This process leads to the release of methanol, citizen, and phenylalanine.
The metabolism of methanol began with the liver, first oxidized into formaldehyde, and then was oxidized into methic acid again.In addition to direct damage to the liver, formaldehyde is also directly toxic for liver cells and is related to carcinogenic characteristics.
Some studies investigated Asba’s sweet carcinogenic potential.For example, a research on rats found that in early life, contacting Asba sweets increases the risk of cancer.
A large number of internal and in vitro studies have shown the potential role of Asba’s sweetness in the development of cancer, leading to many regulatory agencies, such as IARC, and re -considering the safety of Asba sweets for human consumption.Similarly, the results of these studies also support human research, and human research is largely scarce.
In a recent research on the French population, researchers reported that large doses of Asba’s sweetness can slightly increase the risk of related cancer. Researchers pointed out that the risk of breast cancer and obesity -related cancers of these people is particularly particularly risky.High, including colorectal cancer, gastric cancer, liver cancer, oral cancer, pharyngeal cancer, laryngeal cancer, esophageal cancer, ovarian cancer, endometrial cancer and prostate cancer.
These discoveries support the unique impact of Asba sweet on specific cancer risks.Although Asta does not seem to affect the risk of pancreatic cancer, the risk of non -Hodgkin lymphoma and multi -myeloma who eats Asba’s sweetness seems to be greater.
The expected IARC ruling may arouse consumers’ concerns about Asba’s sweet product consumption.Therefore, in addition to reducing or eliminating consumption of Asba sweet products to reduce the risk of cancer, consumers will also be protected to avoid various potential health effects of Asba sweet.
Teratogenicity
During pregnancy, the mother must maintain a healthy diet to ensure the normal development of the fetus and the overall health of the mother.Previous studies have shown that ASW intake during pregnancy may increase the risk of fetal premature birth and allergic diseases.
Many internal studies have also reported various teratogenic effects related to consumption of Asba’s sweetness during pregnancy. Some of them include bad glucose and insulin tolerance, changes in the composition of intestinal microorganisms, weight gain, and infant 2 diabetes.The risk of cardiovascular disease, non -alcoholic fatty liver disease and hormone -related cancers increase.
Behavior
Various nervous systems are attributed to Asba’s sweet exposure. Some of them include nerve and behavioral disorders, as well as some nerve mental reactions, including headaches, convulsions and depression.These influences are mainly due to the sweet metabolism of Asba, which leads to the production of benzyladine, winter and methanol. All of them can pass through the blood and brain barrier and directly interact with neurotransmitters.
In addition to the direct impact of Asba sweet on the central nervous system (CNS), its interaction with the intestinal microorganisms may also help long -term behavior changes.The changes in these microbiological groups also increase the release of corticone and adrenal corticosteroids (ACTH).
After reading these introductions above, I believe that many friends may feel that Asba is a "flood beast". With so many harms, in fact, whether you can drink it for sugar -free drinks, you don’t have to worry too much.Putting the dosage of toxicity is a hooligan. "
As mentioned earlier, the daily acceptable intake of Asba sweet is 50 mg/kg. A 60 kg adult, the daily acceptable Asba sweet intake is 3000 mg, while the sweetness of Asba is sweet is the sweetness ofA highly sweet substitute, for the sugar -free cola, the amount of Asba’s sweetness is 184mg in a can. Calculated in this dose, drink at least 16.3 cans of cola every day, and the intake is only available.Calculate exceeding the standard.
What is the amount of methanol that may be harmful to human health when entering the descendants of human health?Only 10%are about 18 mg. The 18 mg dose of methanol may not be high compared to the methanol that is intake through other diets in daily life.
Therefore, in summary, we can see that although Asba Tiantian was listed by the WHO as a possible carcinogenic substance. This evaluation is only to remind everyone to use sugar -free drinks and foods with sugar.It may also bring health risks. We should recognize this kind of health risk and control ourselves in the intake of this sweet diet, not to completely eliminate it. Occasionally drink a bottle of sugar cola.Not big, you don’t have to worry too much at all. As long as you drink water every day, you don’t have to worry too much.
If you want to keep healthy, whether it is a sugar -containing drink or a "sugar -free drink" that is added with sugar, you should have control. You can drink less and drink less, and drink plenty of boiled water.What about it?
references:
[1] CZARNECKA, K., PILARZ, A., Rogut, A., et al. (2021). ASPARTAME -TRUE OR FALSE? Narrate Review of Safety Analysis of General Use in Products. Nutri. ENTS 13 (6). Doi:10.3390/NU13061957.
[2] DEBRAS, C., Chazlas, E., SROUR, B., et al. (2022). Artificial Sweeteners and CANCER RISK: Results from the Nutricine Population-Based Cohort Study . Plos Medicine. Doi: 10.1371/Journal.pmed.1003950.
“Can sugar -free drinks still drink with confidence”
