Can pregnant mothers take antibacterial drugs?

[Li Kunwen, Department of Pharmacy, Third Affiliated Hospital of Zhengzhou University]

As a special crowd, pregnant mothers have received special attention.Due to the adverse effects of antibacterial drugs on the fetus, pregnant women must choose antibacterial drugs with caution during pregnancy.Clinically, antibacterial drugs are generally divided into three categories: use, cautious and disabled.

1. Antibacterial drugs that can be used during pregnancy

1. penicillin, cephalotinin

The principle of such antibacterial drugs is to hinder the synthesis of bacterial cell walls, while mammals have no cell walls, so they do not cause fetal malformations and small side effects on the human body.Such as penicillin, amoxicillin, cephalipine, cefklo, etc.

2. Macalent ester antibacterial drugs

This type of antibacterial drugs are bacteriostatic agents. They are effective for general respiratory tract infections and mycoplasma, chlamydia, toxoplasty, and low toxicity and small perverted reactions. They are antibacterial drugs that can be used safely during pregnancy.Such as Azithromycin, erythromycin.

2. Antibacterial drugs that need to be used carefully during pregnancy

1. Metronidazole used to be considered as avoiding use during pregnancy. It is now attributed to the American FDA as a medication during pregnancy. It does not increase the danger of fetal terators. Pregnant women can use it, but try to avoid use for 3 months of pregnancy.

2. Local fungal drugs, such as climozole and mimanzole, it is best not to use vagina within 3 months of pregnancy, because the embryo has not developed at this time, the vaginal plug drugs can easily cause miscarriage, and it is safer to use in the later pregnancy.Essence

3. Antibacterial drugs that need to be disabled during pregnancy

1. Antibacterial antibacterial drugs have ear and kidney toxicity, which can cause newborn hearing impairment.

2. Chlorophytyin can accumulate in the body through the placenta, which will cause "gray baby syndrome" characterized by neonatal insufficiency, full body, and abdominal distension.

3. Sulfa drugs can cause neonatal nuclear jaundice.

4. Tetracycline can affect the dysplasia of fetal skeletal and cause the tooth to become gray and yellow (commonly known as "tetracycline teeth").

5. Antibacterial antibacterial drugs can cause arthrocytosis of young animals and affect cartilage development.

6. Oral antifungal drugs, such as ketonazole, anxole and other animal experiments, have teratogenic effects, so pregnant women disable oral antifungal drugs.

When pregnant women choose antibacterial drugs, we should weigh the advantages and disadvantages. According to the degree of infection and different pregnancy periods, the amount and duration of antibacterial drugs are reasonably selected.Reduce to the minimum to ensure the safety of maternal and infants.

(Source: Ministry of Pharmacy of the Third Affiliated Hospital of Zhengzhou University. Disclaimer: If this picture involves copyright issues, please contact Xiaobian to delete in time.)

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